Nouveau, S., Bastien, P., Baldo, F., de Lacharriere O. View abstract. Eur J Endocrinol 2004;151:1-14. The effect of eight weeks of supplementation with, Gardner Z, McGuffin M, eds. Alternative Medicine Alert 2001;4(4):37-48. Stearns DM, Belbruno JJ, Wetterhahn KE. Quercetin is a polyphenolic flavonol that is naturally present in a variety of fruits (such as apples), vegetables (such as onions), and beverages (such as wine and, especially, tea). View abstract. Martin, W. R. and Fuller, R. E. Suspected chromium picolinate-induced rhabdomyolysis. Most of the studies in this review included young men aged 18–25 years who took 1.6–6.4 g/day beta-alanine supplements (in two to four separate servings) over 4–8 weeks. Clin Endocrinol (Oxf) 2007;66:426-33. In 2013, FDA declared products containing this ingredient to be illegal after it received 86 reports of deaths and illnesses associated with dietary supplements containing DMAA. WebMD does not provide medical advice, diagnosis or treatment. S. Klein. [, Braakhuis AJ, Hopkins WG. Int.J Clin.Pharmacol.Res. Creatine monohydrate, which is 88% creatine by weight, is the most widely used and studied form [112,114,123]. Protein is necessary to build, maintain, and repair muscle. 1978;24(4):541-544. Dorgan, J. F., Reichman, M. E., Judd, J. T., Brown, C., Longcope, C., Schatzkin, A., Forman, M., Campbell, W. S., Franz, C., Kahle, L., Taylor, P. R. Relation of energy, fat, and fiber intakes to plasma concentrations of estrogens and androgens in premenopausal women. View abstract. FDA News Release: FDA approves Intrarosa for postmenopausal women experiencing pain during sex. Romanutti, C., Bruttomesso, A. C., Castilla, V., Bisceglia, J. Rasmussen, K. R., Arrowood, M. J., and Healey, M. C. Effectiveness of dehydroepiandrosterone in reduction of cryptosporidial activity in immunosuppressed rats. Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.JAMA 2004;292:2243-8. Arch.Intern.Med 7-14-2008;168:1470. Diabetes Care 2006;29:1826-32. Med Sci Sports Exerc 2006;38:660-6. A dose-response and meta-analysis of dehydroepiandrosterone (DHEA) supplementation on testosterone levels: perinatal prediction of randomized clinical trials. For more information about dietary supplement regulation, see the ODS publication, Dietary Supplements: What You Need to Know. Note: In this case, superscript number 5 implies a reference specific to that part of the sentence which precedes the em dash. Clin Endocrinol. Mech.Ageing Dev. 2020;194(2):313-320. There are no safety data on use of the supplement for more than 1 year [54,60]. Found inside – Page 353Time to wound closure in trauma patients with disorders in wound healing is shortened by supplements containing antioxidant micronutrients and glutamine: a PRCT. Clin Nutr. ... Gandhi A, Beam HA, O'Connor JP, Parsons JR, Lin SS. Romero, R. A., Salgado, O., Rodriguez-Iturbe, B., and Tahan, J. E. Blood levels of chromium in diabetic and nondiabetic hemodialysis patients. Am J Clin Nutr 2009;90:1-10. Reprod Biol Endocrinol. Found inside – Page 58Clin Chimica Acta 394:47–53 Palmer CD, Lewis ME Jr, Geraghty CM, Barbosa F Jr, Parsons PJ (2006) Determination of lead, ... Metallomics 6:960–977 Pinero DJ, Connor JR (2000) Iron in the brain: an important contributor in normal and ... View abstract. Mattson, L. A., Cullberg, G., Tangkeo, P., Zador, G., and Samsioe, G. Administration of dehydroepiandrosterone enanthate to oophorectomized women--effects on sex hormones and lipid metabolism. View abstract. Hayashi T, Teiji Esaki T, Emiko Muto E, et al. Uusitupa MI, Kumpulainen JT, Voutilainen E, et al. Plasma chromium and chromium excretion in diabetes. The National Collegiate Athletic Association and the World Anti-Doping Agency ban the use of DHEA [105,128]. Arthritis Rheum 1992;35 (suppl):S207. Effects of creatine supplementation on performance and training adaptations. J Clin Endocrinol Metab 2005;90:3550-9. Arthritis Rheum. View abstract. Int J Prev Med 2013;4:S53-S7. Ruckert, C., Stuepp, Cdos S., Gottardi, B., Rosa, J., Cisilotto, J., Borges, F. P., Rosemberg, D. B., Bogo, M. R., Tasca, T., De Carli, G. A., and Bonan, C. D. Trichomonas vaginalis: dehydroepiandrosterone sulfate and 17beta-estradiol alter NTPDase activity and gene expression. Bloch M, Schmidt PJ, Danaceau MA, et al. The society states that bepnefits increase after 4 weeks, when muscle carnosine concentrations rise by 40–60% [54]. In contrast, the International Society of Sports Nutrition (ISSN) concluded from its literature review that beta- alanine supplements (4–6 g/day consumed for at least 2–4 weeks) can improve high-intensity exercise performance that lasts over 60 seconds, especially in time-to-exhaustion tasks [54]. Eur J Endocrinol 2001;145:457-61.. Barrett-Connor E, von Muhlen D, Laughlin GA, Kripke A. Endogenous levels of dehydroepiandrosterone sulfate, but not other sex hormones, are associated with depressed mood in older women: the Rancho Bernardo Study. about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. Executive summary of NIH workshop on the use and biology of energy drinks: current knowledge and critical gaps. Neuroendocrinology 1999;70:431-438. One systematic review and meta-analysis to determine whether iron treatments (provided orally or by injection) improved iron status and aerobic capacity in iron-deficient but non- anemic endurance athletes identified 19 studies involving 80 men and 363 women with a mean age of 22 years. 2009;9:168-172. Am J Clin Nutr. 2011;25(3):149-153. Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men. Dehydroepiandrosterone (DHEA) treatment of depression. Obesity. Barnhart KT, Freeman E, Grisso JA, et al. Curr Ther Res 1996;57:747-56. Antioxidants in Sport Nutrition. Biological Trace Element Research 1986;9:197-205. View abstract. Ann N.Y.Acad Sci 1995;774:281-90. Scientific verdict still out on DHEA. J Clin Pharmacol 1999;39:327-48. Effects of acute chromium supplementation on postprandial metabolism in healthy young men. Hum Reprod. Gomez-Santos, C., Hernandez-Morante, J. J., Tebar, F. J., Granero, E., Garaulet, M. Differential effect of oral dehydroepiandrosterone-sulphate on metabolic syndrome features in pre- and postmenopausal obese women. In one study, 10 healthy young men (ages 19–29 years) took a single 100-mg dose of androstenedione. J Rheumatol 1998;25:285-9. Such a large intake of sodium with fluid can lead to temporary hyperhydration, which could be useful in activities where large sweat losses might otherwise lead to significant fluid deficits. Shapiro, K. and Gong, W. C. Natural products used for diabetes. Hirshman, E., Wells, E., Wierman, M. E., Anderson, B., Butler, A., Senholzi, M., Fisher, J. Efficacy: The research to support supplemental citrulline as an ergogenic aid is limited and conflicting at best. Corrigan, A. Farrokhian A, Mahmoodian M, Bahmani F, Amirani E, Shafabakhsh R, Asemi Z. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Arthritis Rheum 1994;37:1305-10. Found inside – Page 112Julie M. Parsons, Anne Chappell. He also supplements his father's picture of his own experiences of being parented as a child, describing how his parents prioritised their own social life over their children, 'we were sort of (pause) ... Int J Sport Nutr Exerc Metab 2013;23:522-32. Nestler, J. E., Beer, N. A., Jakubowicz, D. J., Colombo, C., and Beer, R. M. Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men. Chromium supplementation and resistance training: effects on body composition, strength, and trace element status of men. Aging Cell 2012;11:876-84. Wolkowitz, O. M., Reus, V. I., Roberts, E., Manfredi, F., Chan, T., Ormiston, S., Johnson, R., Canick, J., Brizendine, L., Weingartner, H. Antidepressant and cognition-enhancing effects of DHEA in major depression. Metformin increases total homocysteine levels in non-diabetic male patients with coronary heart disease. Int J Sport Nutr Exerc Metab 2015;25:417-26. Ali, A., Ma, Y., Reynolds, J., Wise, J. P., Sr., Inzucchi, S. E., and Katz, D. L. Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus. World J Urol. 2009;16:272-278. B. Mazza E, Maccario M, Ramunni J, et al. Shock 1997;7:55-59. Sellers claim that dozens of ingredients in dietary supplements can enhance exercise and athletic performance. Some athletes use glutamine supplements in the hope that they will attenuate exercise-induced immune impairment and reduce their risk of developing upper respiratory tract infections. Although products marketed as dietary supplements containing DMAA are illegal in the United States, discontinued, reformulated, or even new products containing DMAA might still be found in the U.S. marketplace. Steroids 2000;65:98-102. Eur J Endocrinol 2011;165:293-300. van Thiel, S. W., Romijn, J. Lancet 1995;346:270-4. View abstract. Med J Aust 8-16-1999;171:206-208. Some NSAIDs include ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene), aspirin, and others. J Int Soc Sports Nutr 2016;13:22. J Rheumatol 2005;32:1336-40. A Pilot Study Employing Dehydroepiandrosterone (DHEA) in the Treatment of Chronic Fatigue Syndrome. Nutr.Clin.Pract. J Infect.Dis 1993;167:830-840. Campbell W, Joseph L, and Davey S. Effects of resistance training and chromium picolinate on body composition and skeletal muscle in older men. Nath R, Minocha J, Lyall V, and et al. Diabetes Care 2005;28:712-3. Taking more, however, is unlikely to improve performance further and increases the risk of side effects. Mertz W. Interaction of chromium with insulin: a progress report. Wearing a dinner jacket, he was suspended hundreds of feet above the ground as he climbed up a ladder dangling from a pod … [, Res PT, Groen B, Pennings B, Beelen M, Wallis GA, Gijsen AP, Senden JM, van Loon LJ. View abstract. Chromium might help keep blood sugar levels normal by improving the way our bodies use insulin. Drake, T. C., Rudser, K. D., Seaquist, E. R., and Saeed, A. Chromium infusion in hospitalized patients with severe insulin resistance: a retrospective analysis. Appl.Physiol Nutr Metab 2008;33:429-433. Eur J Endocrinol 2000;142:466-471. A., Schlicker, S., and Poos, M. Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. [, Mora-Rodriguez R, Pallarés JG. Cerulli J, Grabe DW, Gauthier I, et al. Dehydroepiandrosterone replacement administration: pharmacokinetic and pharmacodynamic studies in healthy elderly subjects. Practical considerations for bicarbonate loading and sports performance. A., Dhatariya, K., Klaus, K. A., Hartman, S. J., McConnell, J. P., Nair, K. S. Effect of dehydroepiandrosterone replacement on lipoprotein profile in hypoadrenal women. Licorice Taking licorice increases levels of DHEA in the body. J Clin Endocrinol.Metab 2010;95:4985-4992. A., Bijlsma, J. W., Derksen, R. H. Effect of dehydroepiandrosterone administration on fatigue, well-being, and functioning in women with primary Sjogren syndrome: a randomised controlled trial. Promotion of chromium absorption by ascorbic acid. Bonorden, M. J., Greany, K. A., Wangen, K. E., Phipps, W. R., Feirtag, J., Adlercreutz, H., Kurzer, M. S. Consumption of Lactobacillus acidophilus and Bifidobacterium longum do not alter urinary equol excretion and plasma reproductive hormones in premenopausal women. View abstract. Dhatariya, K., Bigelow, M. L., and Nair, K. S. Effect of dehydroepiandrosterone replacement on insulin sensitivity and lipids in hypoadrenal women. J Int Soc Sports Nutr 2013;10:1. A randomized, controlled trial. 2001;16:1537-1539. Thomas, V. L. and Gropper, S. S. Effect of chromium nicotinic acid supplementation on selected cardiovascular disease risk factors. 1991;19:128-131. A physiologically based model for the ingestion of chromium(III) and chromium(VI) by humans. B. J Clin Endocrinol Metab 2000;85:3208-17. Br J Obstet Gynaecol 1982;89:195-8. Rheum Dis Clin North Am 2000;26:349-62. Stangl, B., Hirshman, E., and Verbalis, J. 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The Australian Institute of Sport supports the use of bicarbonate for improving sports performance in suitable athletic competitions under the direction of an expert in sports medicine, but it notes that more research might be required to understand how the supplement should be used for best results [29]. Sawalha, A. H. and Kovats, S. Dehydroepiandrosterone in systemic lupus erythematosus. J Neurol Neurosurg Psychiat 1960;23:52-5. Low levels of sugar in the blood (hypoglycemia). PremesisRx. Metabolism 1996;45:1011-5. Psychiatry Res 2012;200(2-3):544-9. Phillips, A. C., Carroll, D., Gale, C. R., Lord, J. M., Arlt, W., and Batty, G. D. Cortisol, DHEA sulphate, their ratio, and all-cause and cause-specific mortality in the Vietnam Experience Study. 2012,9:33. A study in 15 resistance-trained men found no differences among those taking 3.21 mg/kg Tribulus terrestris or placebo for 8 weeks in improvements in bench and leg press scores or in muscle mass [194]. 2009;19:499-503. D.S.K declares that in part, he works for a contract research company that conducts research and human clinical trials for industries including dietary supplements, medical foods, beverages, foods, pharmaceuticals and medical devices. Am J Med Sci. Adams, J. J Clin Biochem.Nutr 2008;43(3):191-198. J Psychiatr.Res 2010;44:215-219. Zhang M, Niu W, Wang Y, et al. At doses of 9–30 g/day, the most commonly reported adverse reactions are gastrointestinal discomfort, such as diarrhea and nausea, and slightly reduced blood pressure [33,36,37]. View abstract. Int J Neuropsychopharmacol 2000;3(4):311-314. Glucose and insulin responses to dietary chromium supplements: a meta-analysis. [, Ganio MS, Klau JF, Casa DJ, Armstrong LE, Maresh CM. White, T., Jain, J. K., Stanczyk, F. Z. Clin Endocrinol (Oxf) 2000;52:775-80. The Physician and Sportsmedicine 1992;20(3):189-193, 196, 198. Protein ingestion before sleep improves postexercise overnight recovery. Krieger D, Krieger S, Jansen O, et al. J Am.Coll.Nutr. B. Dehydroepiandrosterone and sport. Maturitas 7-20-2009;63:240-245. Found inside – Page 163... Practical Wild Fowling net 60 L. U. Gill Family , The , Parsons .net 12 6 Putnam's Sons Herald Supplements , Vol . ... The ..net 26 Routledge Gas Engineer's Pocket Book , The , O'Connor .net 10 6 Lockwood Genung ( J. F. ) The Hebrew ... The UL of vitamin E, at 800 mg/day for adolescents and 1,000 mg/day (1,100–1,500 IU) for adults, is likewise higher than the dose that these studies typically used [26]. Pharmacotherapy 2001;21:647-51.. View abstract. Sci.Total Environ. J Trace Elem Exp Med 1999;12(2):91-97. Kelly GS. [, Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. J Gerontol.A Biol.Sci Med Sci 2000;55(5):M260-M263. Effects of an amylopectin and chromium complex on the anabolic response to a suboptimal dose of whey protein. Diabetes 1997;46(suppl 1):55A. Rajpathak S, Rimm EB, Li T, et al. Wise, J. 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Dehydroepiandrosterone activates endothelial cell nitric-oxide synthase by a specific plasma membrane receptor coupled to Galpha(i2,3). Stanczyk, F. Z., Slater, C. C., Ramos, D. E., Azen, C., Cherala, G., Hakala, C., Abraham, G., and Roy, S. Pharmacokinetics of dehydroepiandrosterone and its metabolites after long-term oral dehydroepiandrosterone treatment in postmenopausal women. J Am Geriatr Soc 2010;58:1707-14. Is supplementation required? Fitzpatrick, J. L., Ripp, S. L., Smith, N. B., Pierce, W. M., Jr., and Prough, R. A. Metabolism of DHEA by cytochromes P450 in rat and human liver microsomal fractions. Arthritis Rheum 2004;50:2858-68. Chen, Y. C., Chang, H. H., Wen, C. J., Lin, W. Y., Chen, C. Y., Hong, B. S., and Huang, K. C. Elevated serum dehydroepiandrosterone sulphate level correlates with increased risk for metabolic syndrome in the elderly men. Mayo Clin Proc 2008;83:1218-25. Supplementation with creatine over weeks or months helps training adaptations to structured, increased workloads over time. Overall, it suggests that doses of 2–20 g/day arginine have little to no effect on performance in either anaerobic or aerobic exercise [30,31]. View abstract. Colker C, Torina G, Swain M, and et al. Surgery 2001;130:947-53.. Calhoun KE, Pommier RF, Muller P, et al. Tagliaferro, A. R., Ronan, A. M., Payne, J., Meeker, L. D., and Tse, S. Increased lipolysis to beta-adrenergic stimulation after dehydroepiandrosterone treatment in rats. Hammer, F., Subtil, S., Lux, P., Maser-Gluth, C., Stewart, P. M., Allolio, B., and Arlt, W. No evidence for hepatic conversion of dehydroepiandrosterone (DHEA) sulfate to DHEA: in vivo and in vitro studies. Virus Res 2008;135:203-212. B-alanine supplementation for athletic performance: an update. Anderson RA. 2020. Neurology 2008;71:407-12. Brown GA, Vukovich MD, Reifenrath TA, et al. Ann N.Y.Acad.Sci. J Clin Rheumatol 1999:5:56-9. It is therefore difficult to predict what, if any, benefits an exercising individual might experience from consuming HMB. Rev Fr.Endocrinol Clin 1966;7:383-387. View abstract. J Psychiatr.Pract. Effects of chromium picolinate supplementation on body composition: a randomized, double-masked, placebo-controlled study. Cochrane Database Syst Rev 2013;11:CD010063. Iron balance is an important consideration for athletes who must pay attention to both iron intakes and iron losses. 2008;28:942-943. Labrie, F., Archer, D. F., Bouchard, C., Fortier, M., Cusan, L., Gomez, J. L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dube, R., Cote, I., Labrie, C., Lavoie, L., Berger, L., Gilbert, L., Martel, C., Balser, J. Intravaginal dehydroepiandrosterone (prasterone), a highly efficient treatment of dyspareunia. Strous, R. D., Maayan, R., Kaminsky, M., Blumensohn, R., Weizman, A., and Spivak, B. DHEA and DHEA-S levels in hospitalized adolescents with first-episode schizophrenia and conduct disorder: a comparison study. A., Meseguer, I., Mateos-Vega, C. J., Gonzalez-Munoz, M. J., de Bustos, F., Gomez-Escalonilla, C., Ort-Pareja, M., Zurdo, M., and Martinez-Para MC. Am J Psychiatry 1999;156:646-9. BCAAs make up approximately 25% of the amino acids in foods containing complete proteins (including all essential amino acids) [72]; most of these foods are animal products, such as meat, poultry, fish, eggs, and milk (see section on protein).
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